Adobe Caslon Pro generates enormous PDF files on Mac Word, displays incorrectly on Word for Windows

Had a terrible experience trying to typeset my first document with Adobe Caslon Pro in Word. In Word Mac, 27 page all text document rendered to 70 MB PDF with Opentype features enabled, well under a megabyte with Opentype features disabled in compatibility settings for the same font. Opening same document in Word for Windows (both 2010 and 2013) displayed with incorrect (increased) line spacing and Opentype features (e.g. ligatures) disabled even though they were enabled in compatibility setting (they showed up when I opened the same document in Mac).